張召鋒

老年營養、營養與疾病、精準營養

1🦻🏻、國家自然科學基金面上項目（基於腸道菌群為靶點探討燕麥葡聚糖延緩糖尿病腎病進展的機理研究）

2☎、國家自然科學基金青年項目（原花青素減少2型糖尿病腎病發生及抗炎機製研究）

3、教育部博士點基金（低聚原花青素改善高糖狀態下足細胞裂孔隔膜結構和功能的分子機製）

4、達能營養中心膳食營養研究與宣教基金（植物甾醇對我國高膽固醇血症患者的幹預研究）

5🧰、橫向課題：葉黃素和玉米黃質對藍光損傷視網膜黃斑變性的作用及機製研究

6👩🏿‍💻、橫向課題👃🏼：燕麥麩調控糖脂代謝的作用及機製研究

7、橫向課題：發酵黃芪降尿酸的作用及機製研究

8👐、橫向課題：羊乳清蛋白和羊乳酪蛋白對少肌症的影響及作用機製研究

9、橫向課題：羊乳全脂粉和羊乳低脂粉對少肌症的影響及作用機製研究

1) Zhaofeng Zhang, Yujie Li, Yong Li. Grape seed proanthocyanidin extracts prevent hyperglycemia-induced monocyte adhesion to aortic endothelial cells and ameliorates vascular inflammation in high-carbohydrate/high-fat diet and streptozotocin-induced diabetic rats. Int J Food Sci Nutr. 2015 Aug;67(5):524-34.

2) Li Zhang, Jiao Yang, Zhangyi Liao, Xiaomeng Zhao, Xuefeng Hu, Wenli Zhu, Zhaofeng Zhang*.  Association between Diabetes and Cognitive Function among People over 45 Years Old in China: A Cross-Sectional Study. Int J Environ Res Public Health. 2019 Apr 11;16(7)

3) Xiaxia Cai, Lei Bao, Jinwei Ren, Yong Li, Zhaofeng Zhang*. Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1α axis in vitro. Food Funct. 2016 Feb;7(2):805-15

4) Lei Bao, Xiaxia Cai, Zhaofeng Zhang*, Yong Li*. Grape seed procyanidin B2 ameliorates mitochondrial dysfunction and inhibits apoptosis via the AMP-activated protein kinase-silent mating type information regulation 2 homologue 1-PPARγ co-activator-1α axis in rat mesangial cells under high-dose glucosamine. Br J Nutr. 2015 Jan 14;113(1):35-44.

5) Lei Bao, Xiaxia Cai, Xiaoqian Dai, Ye Ding, Yanfei Jiang, Zhaofeng Zhang*, Yong Li. Grape seed proanthocyanidin extracts ameliorate podocyte injury by activating peroxisome proliferator-activated receptor-γ coactivator 1α in low-dose streptozotocin-and high-carbohydrate/high-fat diet-induced diabetic rats. Food Funct. 2014 Aug;5(8):1872-80

6) Sumiya Aihemaitijiang, Yaqin Zhang, Li Zhang, Jiao Yang, Chen Ye, Mairepaiti Halimulati, Wei Zhang, Zhaofeng Zhang*. The Association between Purine-Rich Food Intake and Hyperuricemia: A Cross-Sectional Study in Chinese Adult Residents. Nutrients. 2020 Dec 15;12(12):3835.

7) Chen Ye, Xiaojie Huang, Ruoyu Wang, Mairepaiti Halimulati, Sumiya Aihemaitijiang, Zhaofeng Zhang*. Dietary Inflammatory Index and the Risk of Hyperuricemia: A Cross-Sectional Study in Chinese Adult Residents. Nutrients. 2021 Dec 16;13(12):4504.

8) Yaqin Zhang, Jiao Yang, Ninghua Huang, Linyan Xiao, Hong Lin, Jiayou Luo, Zhaofeng Zhang*, Zhiyong Zou*. Changes in breast milk lutein concentrations and their associations with dietary lutein intake: a 12-week prospective analytical study. Br J Nutr. 2019 Nov 14;122(9):1033-1039.

9) Chen Ye, Sumiya Aihemaitijiang, Ruoyu Wang, Mairepaiti Halimulati, Zhaofeng Zhang*. Associations between Early-Life Food Deprivation and Risk of Frailty of Middle-Age and Elderly People: Evidence from the China Health and Retirement Longitudinal Study. Nutrients. 2021 Aug 31;13(9):3066.

10) Jiao Yang, Dankang Li, Yaqin Zhang, Li Zhang, Zhangyi Liao, SuMiYa Aihemaitijiang,Yanmei Hou, Zhijun Zhan, Kui Xie, Zhaofeng Zhang*. Lutein Protects the Retina from Blue LED light-Induced Degeneration by Inhibiting Increasing Oxidative Stress and Inflammation. Journal of Functional Foods. 2020(73): 104107