王旗

1.細胞與計算毒理學：中藥成分毒性的早期預測

2.藥物毒理學：藥物代謝和毒性機製

3.生態毒理學：自然環境中大氣汙染物對人體健康的影響

1. 2022-2025年，國家自然科學基金面上項目（82174068）✝️：基於靶點“鉤釣”技術的朱砂靶蛋白發現和神經藥理/毒理機製研究，項目負責人

2. 2019-2021年，國家重點研發計劃課題（2018YFC1004301）🧔🏻‍♀️：基於外暴露監測的環境和行為因素對胚胎發育與妊娠影響的隊列研究，課題負責人

3. 2017-2020年，國家自然科學基金面上項目（81673685）🤹🏽：小兒中成藥“一撚金”中朱砂的潛在神經發育毒性及配伍減毒研究📶，項目負責人

4. 2014-2016年🧚🏽‍♀️，教育部博士點基金 (20130001110065)：補骨脂酚CYP代謝與毒性的分子機製研究💇🏽‍♂️，項目負責人

5. 2014年🕺，國家自然科學基金主任基金(81341089)：基於代謝相互作用的補骨脂-甘草配伍的適宜性研究💆🏼‍♀️，項目負責人

6. 2008-2011年，國家科技支撐計劃重大項目(2007BAC03A10)🥋🔖：“執行<聯合國防治荒漠化公約> 的支撐技術研究與示範”專題“風沙災害對人體健康的影響評價”，專題負責人

7. 2007-2009年，國家自然科學基金(30672653)：朱砂在消化道中物種轉化與藥效毒性相關性研究，項目負責人

1. Zhang T, Wang S, Li L, Zhu A, Wang Q*. Associating diethylhexyl phthalate to gestational diabetes mellitus via adverse outcome pathways using a network-based approach. Sci Total Environ. 2022, 824:153932

2. Yuqing Sun, Xin Zhang, Xiaofan Shen, Shuo Wang, Qi Wang*, Xiuwei Yang *. Computational and experimental characterization of isomers of escin-induced renal cytotoxicity by inhibiting heat shock proteins. Eur J Pharmacol, 2021, 908:174372

3. Jingwei Zhao, An Zhu, Yuqing Sun, Wenjing Zhang, Tao Zhang, Yadong Gao, Danping Shan, Shuo Wang, Guojun Li, Kewu Zeng*, Qi Wang*, Beneficial effects of sappanone A on lifespan and thermotolerance in Caenorhabditis elegans. Eur J Pharmacol, 2020, 888: 173558

4. Mimi Yang, Lichao Wang, Tao Zhang, An Zhu, Yuqing Sun, Jingwei Zhao, Dan Liu, Qi Wang*, Kewu Zeng*. Different proteomic profiles of cinnabar upon therapeutic and toxic exposure reveal distinctive biological manifestations. J Ethnopharmacol, 2020, 112668.

5. An Zhu, Zonghui Ji, Jingwei Zhaoa, Wenjing Zhangb,c, Yuqing Suna, Tao Zhanga, Shan Gaob, Guojun Li*, Qi Wang*. Effect of Euphorbia factor L1 on intestinal barrier impairment and defecation dysfunction in Caenorhabditis elegans. Phytomedicine，2019, 65: 153102

6. Jinlan Yang, An Zhu, Shuo Xiao, Tao Zhang, Liming Wang, Qi Wang*, Lifeng Han*. Anthraquinones in the aqueous extract of Cassiae semen cause liver injury in rats through lipid metabolism disorder. Phytomedicine🌃，2019, 64: 153059

7. Yuqing Sun, Shaoze Shi, Yaqiu Li, Qi Wang*. Development of quantitative structure-activity relationship models to predict potential nephrotoxic ingredients in traditional Chinese medicines. Food Chem Toxicol, 2019, 128: 163-170

8. An Zhu, Yuqing Sun, Qianwen Zhong, Jinlan Yang, Tao Zhang, Jingwei Zhao, Qi Wang*. Effect of Euphorbia factor L1 on oxidative stress, apoptosis and autophagy in human gastric epithelial cells. Phytomedicine，2019, 64: 152929 

9. An Zhu, Tao Zhang, Qi Wang*. The phytochemistry, pharmacokinetics, pharmacology and toxicity of Euphorbia semen. J Ethnopharmacol, 2018, 227: 41-55  

10. Xiaojing Hu, Youbo Zhang, Lei Zhang, Qi Wang*, Xiu-Wei Yang*. Metabolic detoxification of bakuchiol is mediated by oxidation of CYP 450s in liver microsomes. Food Chem Toxicol, 2018, 111: 385-392